Programs

Flagship programs

Specialist programs

Professional Voice

The program

Resources

Conditions & Treatments

Voice disorders

Other conditions

Treatments

International Patients

Access

Your visit

Education & Research

Education

Research

About

About the institute

Contact
Request an Appointment

+90 216 606 16 48 · info@istanbulvoicecenter.com

Kadıköy, İstanbul · Monday to Saturday, 09:00 to 18:00

Conditions

R-CPD: the inability to belch

Retrograde cricopharyngeal dysfunction, or R-CPD, is a condition in which a person cannot belch. It is under-recognised, often lifelong, and treatable.

Consultation with a patient at Istanbul Voice Center

What it is

The cricopharyngeus is a ring of muscle at the top of the oesophagus. It stays closed most of the time and opens to let food down. Normally it also relaxes briefly to let swallowed air back up as a belch. In R-CPD it does not relax in that direction, so air is trapped.

Symptoms

  • inability to belch, often for as long as the person can remember
  • gurgling or croaking noises from the throat and chest
  • bloating and abdominal pressure, worse after meals and fizzy drinks
  • excessive flatulence
  • difficulty vomiting
Consultation desk at Istanbul Voice Center

How it is diagnosed

The diagnosis is mainly clinical: the history is characteristic. Examination helps exclude other causes, and further tests are used when the picture is atypical.

Treatment

Treatment is a botulinum toxin injection into the cricopharyngeus muscle, which allows the belch reflex to establish. The full pathway, including the short visit many international patients need, is on the R-CPD / No-Burp Program page.

Associate Professor Necati Enver, director of Istanbul Voice Center

Medically reviewed by

Associate Professor Necati Enver, MD

Laryngologist · Founder and Director, Istanbul Voice Center · Reviewed September 2026

General information only. It does not replace an individual assessment. Medical disclaimer

FAQ

Frequently asked questions

Why can't I burp?

In retrograde cricopharyngeal dysfunction, the muscle at the top of the oesophagus does not relax to let air escape upward. Air that should leave as a belch is trapped, causing pressure, bloating and gurgling.

Is R-CPD rare?

It was characterised relatively recently and is under-recognised rather than rare. Many people with R-CPD have never been told that the problem has a name.

How is R-CPD treated?

With a targeted botulinum toxin injection into the cricopharyngeus muscle. See our R-CPD / No-Burp Program for the full pathway.

Need a specialist voice or laryngeal evaluation?

Tell us briefly what is happening. We reply with the next step, usually within one business day.